So, now that the world has discovered that its mRNA vaccination experiment has not worked and has led to an abnormal tolerance associated immune response as I explained here, the excuses start pouring in. Some people are in denial and pretend that this abnormal immune response we see in the mRNA vaccinated population, is just a normal inevitable result of exposure to this virus.
And yet, if we look at the most recent study on the topic, the excuses don’t hold up. I don’t want to ignore it and look the other way, when people lie about what they did.
These idiots who peddled these vaccines left people stuck with a broken immune response. The arguments these people peddled, that this immune response is normal, or the inevitable outcome after sufficient exposure to the virus, can be easily refuted based on the studies that are coming out now.
What’s happening now was not inevitable. It’s entirely their fault, caused by their reckless intervention in human biology, that they forced down our throats. They violated the laws. They violated the principle of bodily integrity. They violated the precautionary principle.
But they also violated the most basic principles of immunology. They insulted the work of art they intervened in. Our individual cells have an immune system of their own. But these people injected people’s cells with a synthetic genetic code, that includes synthetic nucleotides not found in the virus itself, that were intended to fool people’s own cells, to prohibit these cells from recognizing what was happening.
This is an insane and dangerous expression of human hubris. Vaccination once began with weak strains of viruses, intended to prepare the immune system against circulating stronger strains. But this is not preparing the immune system. What these people did is an attempt to deceive the immune system, they sought to fool it into doing something it doesn’t want to do on its own accord.
They threatened us with jail sentences, people lost their jobs, people were socially ostracized and threatened with having their children taken away from them, because they did not want to participate in this irreversible unprecedented medical experiment. An experiment that has now clearly dramatically backfired, resulting in millions of deaths. And we have the evidence now to prove it.
We’re still looking at the worst case scenario:
-IgG4 is not part of a normal immune response to SARS-COV-2, as it’s still not seen in the unvaccinated, except during the acute phase in a handful of severe (hospitalized) cases. In healthy unvaccinated people, we still see zero evidence of an IgG4 response to Spike.
-IgG4 still remains the dominant immune response after mRNA vaccination, hundreds of days after the last shot.
-There’s a temporary increase in IgG3 after vaccination, but it almost immediately disappears, leaving just IgG2 and IgG4.
Why is this such a huge problem? Well, I understand if you don’t want to read all the posts I’ve written on this topic, but the short version is that IgG3 is unique in having a long structure that is meant for providing strong neutralization of viral particles. It’s the antibody you want to see in people who are immune to this virus.
IgG2 and IgG4 are meant to help your immune system tolerate things it should not overreact to. IgG2 in particular is meant to help your body tolerate things in your gut, where you have a lot of bacteria that are harmless but look very different from your own cells. Thanks to IgG2, your immune system is not constantly at war with the bacteria in your own gut.
Let’s skip to the juice:
Here you have the results seen in vaccinated people. If you look at B and D, you see that IgG2 and IgG4 gradually become the dominant antibody response, with every vaccination dose increasing the level of these antibodies.
If you compare B and D to C, you see another problem: The normal antibody you’re supposed to be sending after the virus (IgG3) rapidly declines to zero again. On the other hand, IgG2 and IgG4 stick around.
So is any of this normal? That’s what the usual suspects were arguing. They thought that IgG4 is just part of the immune response you eventually end up with, because the body has to shut down excessive inflammation from the SARS-COV-2 infections. But look at the results from this study and you find that this is incorrect. They also studied unvaccinated people who had an infection. Here you see the results they found in unvaccinated people:
They look at 52 unvaccinated people who had been infected by this virus. They find elevated IgG4 or IgG2 as part of the immune response in none of them. Zero. It doesn’t happen. What happens after repeated mRNA vaccination, is not part of a normal immune response to this virus.
But look at something else with me. You see that IgG3 goes up a few days after the infection, but then it goes down again to previous levels. Yet, we have known for a long time that protection against reinfection in the unvaccinated lasts for hundreds of days, along with reduced severity once the reinfection occurs.
That points towards improvements in the innate immune response, as responsible for the protection. These results imply that it’s not the IgG antibody response that is normally supposed to keep people protected after their first infection. Yet, the IgG4 antibodies may very well be taking on that role in the mRNA vaccinated population.
As I have explained before, the situation seems to be worse than first anticipated. We first found these results in people who were vaccinated before ever being infected by the virus. Later studies suggested the mRNA vaccines can also have this effect in people who were vaccinated after their first infection.
And it’s worse. They also find evidence that overall IgG4 produced by the body increases after these mRNA shots, not just specifically the response to the Spike protein:
So why does this matter? These antibodies are capable of neutralizing the virus at high enough concentrations. But there’s one thing they don’t do: They don’t tell the immune system to destroy infected cells. I quote:
IgG4 is largely unable to activate antibody-dependent immune effector responses and, furthermore, undergoes Fab (fragment antigen binding)-arm exchange, rendering it bispecific for antigen binding and functionally monovalent. These properties of IgG4 have a blocking effect, either on the immune response or on the target protein of IgG4.
Binding to most Fcγ receptors is reduced for IgG4 (although not completely abrogated), resulting in IgG4 having poor ADCC activity21,22 and, probably, also ADCP activity (although this has not been studied in detail). Interestingly, binding of IgG4 to the inhibitory receptor FcγRIIb is not affected, which skews Fcγ receptor signalling induced by IgG4 away from cellular activation and towards inhibition.
It preferentially binds to receptors that tell your immune system to shut down. This FcγRIIb receptor is found on your antibody producing B cells, on your T cells (the CD8 killers and the CD4 helpers), but also on your innate immune cells. This includes your basophils and mast cells. It also includes your NK cells, which are supposed to kill cells that look sick.
It’s also found on your macrophages, which clean up cellular debris. It’s also found on your dendritic cells, that go up to your T cells and B cells in your lymph nodes, to show what they found that needs to be deal with. All these cells have this receptor, so all these cells are being told the same message by this IgG4 antibody: This viral protein is not important, don’t worry about it. For the IgG2 antibody, the effect is quite similar.
The IgG4 and IgG2 antibodies may still have some interfering effect on the virus, by binding to the Spike protein. But that’s not enough! After all, these antibodies can not reach everywhere. For example, they’re bad at getting through the blood brain barrier. Most importantly, they can’t enter your cells! So the virus is able to remain in your cells, while these antibodies are telling your whole immune system that the virus is not really something to worry about.
I think I’ve already explained before what effect you would expect this to have: You would expect new mutated versions of the virus to emerge that take advantage of this abnormal behavior most people’s immune systems now have. The most notorious effect you would expect is increased fusogenicity. When the virus infects a cell, it can cause that cell to merge with other cells. That then allows the virus to spread itself into more cells, without ever leaving the protective membrane of the cell that stops antibodies from entering. Fusogenicity is selected for, because it evades neutralizing antibodies.
With the recent BA.2.86 variants, you see that fusogenicity has increased again. This leads to increased severity of the infection, it makes the virus more damaging. What you observed in BA.2.86, is that the Spike protein changed dramatically, while the rest of the virus remained largely the same.
What you also see, as I have illustrated before, is that with the BA.2.86* lineages, we now see record levels of the virus in sewage:
On the other hand, in India, where they did not use the mRNA vaccines, you see that this virus does not lead to very high levels in sewage:
What does this mean?
Well, if the BA.2.86 family represents a step towards adaptation to the mRNA vaccinated population’s abnormal immune response to this virus, this fits what you would expect to see.
And we still have to find out the answer to this question: Do people ever really get rid of the virus after an infection by the BA.2.86 family? Right now, wastewater levels of this virus are still higher in the Netherlands than anything we saw before we began vaccinating people.
The reason SARS2 is able to form these syncytia, with which it can spread from one cell to another without being exposed to people’s antibodies, is because of the Furin cleavage site. Without the Furin cleavage site, it can not create these syncytia.
So what I find remarkable, is that with BA.2.86, we now see for the first time ever, that SARS-COV-2 is further improving its Furin cleavage side, with added Arginine. This never happened before BA.2.86 emerged, but now we see it happening on multiple branches of the BA.2.86 family simultaneously.
These idiots broke people’s immune response. They gave these vaccines to healthy children and teenagers, who were at no risk of dying from this virus. And it looks to me, like SARS-COV-2 is in the process of learning to take advantage of their stupidity.