I have to do one more post about the vaccines. You can see vaccine resistance evolve in real-time, if you bother to look for it. However, most people involved in the vaccine business don’t bother to look for it: They look for ways to massage the data to pretend that it’s not happening. Here’s an example:
It is a GREAT morning when you find studies that can help put to rest concerns about AY.4.2, B.1.617.2+E484K, AY.1, AY.2 (or rather “Delta-Plus” in general) Lambda, B.1.1.519, A.30, Mu and so much more.
When I say the vaccines can handle variants I mean it. Working on a thread.
— Chise 🧬🧫🦠💉🔜 MFF (@sailorrooscout) November 10, 2021
The guy continues:
AY.4.2 recently accounted for an increase proportion of Delta cases in United Kingdom (UK), Romania, Poland, and Denmark. Here, researchers evaluated the sensitivity of AY.4.2 to neutralization by sera from Pfizer recipients. AY.4.2 was NOT more resistant to neutralization
— Chise 🧬🧫🦠💉🔜 MFF (@sailorrooscout) November 10, 2021
And then he shows us this graph:
He says “AY.4.2 is not more resistant to neutralization than other Delta lineages”. If you look at the actual graph, you’ll notice that it does seem to be more resistant. However, it just doesn’t reach statistical significance. The slope should be obvious: Delta was more resistant than the original strain we got in Europe. Delta mutated into AY.4 which was again slightly more resistant. Then AY.4 mutated into AY.4.2, which is again slightly more resistant.
But there are two things to note: When they do a study like this, they just take the variant as defined by the mutations that allow them to group the variants. They don’t look into any further mutations that have emerged within sublineages of the variant. In other words, it’s always looking at the past. At this point, AY.4.2 has given birth to two new sublineages, AY.4.2.1 and AY.4.2.2, both of which again developed new mutations and look like they’re more resistant.
But now you might wonder: Why should I care? It still neutralizes the virus, right? Well, here’s the thing. Imagine you’re a medieval peasant who is sent off to war. You want to bring your morningstar with you, but your wife suggests you bring your pitchfork instead. You would recognize your chances in battle are worse.
Similarly, your body is not a sitting duck for this virus. Your body develops its own antibody response upon exposure to this virus. If however you’re vaccinated with a different strain, it can get stuck with a worse antibody response than it would have developed if it had not been vaccinated before being exposed to this virus. That’s what you need to understand.
And so here’s what happens, when you’re stuck with this poor immune response: Sometimes it’s strong enough to fight off the virus, so you don’t notice your exposure to the virus, as it’s aborted early. When this poor immune response is not sufficient however, you’re stuck with a situation where your body can’t develop the optimal response it could have developed if it hadn’t been exposed to these vaccines. What does that look like? Here’s what that looks like:
Truveta used its COVID-19 study as an example of the platform’s capabilities.
Among its findings:
- About 1% of vaccinated people overall got a breakthrough infection, with 0.1% of the vaccinated general population hospitalized for a breakthrough case.
- 9% to 15% of people who have a breakthrough infection of COVID-19 end up hospitalized, with Pfizer vaccinated patients showing the 9% trend and Johnson & Johnson patients at 15%.
- Of all high-risk conditions studied, patients with chronic kidney disease required hospitalization the most: One in four members of this group wound up hospitalized after a breakthrough infection.
So, ask yourself this: How can you end up with 15% of people vaccinated with Johnson & Johnson ending up hospitalized from this virus upon being infected?
Overall hospitalization risk for this virus is much lower. It should be obvious what’s happening: Most of the time the vaccines protect you from getting infected. When they fail at protecting you against infection however, your body is stuck with such a maladapted immune response that it struggles to clear the virus. If your body had been allowed to learn on its own how to clear this virus, the immune response would have been more efficient and these people would not have had such a high risk of hospitalization.
Sounds far fetched? Well look at this:
In this study we profiled vaccine-induced polyclonal antibodies as well as plasmablast derived mAbs from individuals who received SARS-CoV-2 spike mRNA vaccine. Polyclonal antibody responses in vaccinees were robust and comparable to or exceeded those seen after natural infection. However, the ratio of binding to neutralizing antibodies after vaccination was greater than that after natural infection and, at the monoclonal level, we found that the majority of vaccine-induced antibodies did not have neutralizing activity. We also found a co-dominance of mAbs targeting the NTD and RBD of SARS-CoV-2 spike and an original antigenic-sin like backboost to seasonal human coronaviruses OC43 and HKU1. Neutralizing activity of NTD mAbs but not RBD mAbs against a clinical viral isolate carrying E484K as well as extensive changes in the NTD was abolished, suggesting that a proportion of vaccine induced RBD binding antibodies may provide substantial protection against viral variants carrying single E484K RBD mutations.
If your body is exposed to the whole virus, it has the opportunity to focus on developing an immune response to the easiest bits: The rare few places in this virus where it looks entirely different from anything your own body produces. If it’s only exposed to the spike protein, it has to learn how to deal with this virus, solely by working with the spike protein. This means it’s now just going to deploy a wider arsenal, including many “shitty antibodies”, that it would not bother deploying if it could just focus on easy parts of the nucleocapsid protein and other proteins.
And to make matters worse, the immune system is not just forced to focus entirely on the spike protein. It has to focus on an outdated version of the spike protein, so a large share of the antibodies that it’s forced to use don’t even work the way they are supposed to work anymore. Many of these antibodies now merely enhance the infection, making it easier for viral particles to replicate themselves within your own macrophages.
But let’s return to our furry friend for a moment, to illustrate the problem. Imagine this guy took a look at the data and concluded: “Uh oh, the vaccines are about to backfire!” What do you think would happen to him? His peers in the community would get angry, his employer would say that he’s promoting “vaccine hesitancy” and the people who follow him because they like to feel as if they’re smarter than their racist antivaxxer antimasker uncle Bob will get upset.
This guy is only going to go down one path, because he’s only going to be rewarded for going down one path: He’s going to be a cheerleader for the vaccines. When it does become undeniable that the vaccines don’t work anymore, there will never be a point when he will admit “you were better off never taking any of these vaccines”. Rather, he’s going to say: “Now it’s time for boosters!”
If you want to deny climate change is caused by humans, you can build a career out of that, Big Oil will give you a salary. If you deny that the vaccines against SARS-COV-2 are a good idea, who is going to pay you? Big vitamin D? Big Exercise? I can give you a list of people who became billionaires through these vaccines. These are people who saw their net worth jump tenfold in a year. Most of the people working in these companies receive options too, they all have a stake in hyping their product. How many people can you think of who became billionaires by saying: “these vaccines will probably backfire”? Your career as a scientist is over when you warn about this ongoing mistake.
The other thing to notice is that as this vaccine evading variant named AY.4.2 spreads throughout the UK, all these virologists and vaccine developers who are watching their experiment blow up in their faces in real time still deny what’s happening. “It just has a 10% replication advantage bruh!” Is what they suggest to you.
But here’s the thing: Of course it only has a minor advantage compared to the rest of the strains, because those other strains are also evolving away from our vaccine induced immune response. They’re all developing their own ways of evading the spike-protein based immunity. Some are a little faster than others so you notice them, but the fact that this strain grows slowly doesn’t mean you can pretend it has no significant advantage over its ancestral strain.
There is nothing out there that you, me, or anyone else can say at this point, that will make these people agree that the vaccines were a bad idea. There’s no standard of evidence you can meet that will ever make them change their minds. They will be going into their graves, denying what they did.
It really shouldn’t take a genius to recognize what’s going on. As I’ve said before, 95% of Dutch elderly above the age of 70 are vaccinated. So why are we seeing this:
“When I say the vaccines can handle variants I mean it guis”
“Oh but you can still get infected, you just won’t end up in the hospital!”
Alright cool, so tell me then, why are we seeing this:
It’s one year after we got the big winter wave and the situation looks worse than it did one year ago. People are supposed to have vaccine induced immunity. Those who don’t have vaccine induced immunity should have natural immunity. So how the hell do you end up in basically the exact same situation as last year?
“Well it must be because we relaxed social distancing and because of those handful of conspiracy theorists who refuse to get vaccinated!” Alright cool, how come they’re not dropping dead like flies in Sweden then? It seems to me like it would be useful to ask yourself what they did right. The reason they’re doing relatively well is because a lot of people were exposed to this virus before receiving these “vaccines”. The people who have had (almost) no exposure before receiving these vaccines seem to be the ones in big trouble.
But let’s focus on the crux of the matter. This is what they show you:
And then they try to get you to believe this somehow suggests the vaccine still works, even as your eyes can see the exact opposite. It should be pretty obvious however that the virus has evolved away from the vaccine, leading to the current surges. Any attempt now to deploy boosters is just going to lock in this immune response that no longer works for the long term.
The other thing we need to consider, is that the vaccine cheerleaders will argue that the vaccines still protect against death. You can show them the skyrocketing infection rates, the sort of thing normal vaccines are supposed to prevent and they will tell you that it doesn’t matter, because the vaccines also decrease the severity of the infection, leading to fewer deaths.
But here’s the thing: It has been 1.5 years now. Hospitals have gotten better at treating patients. They’re (hopefully) not going to needlessly put you on a ventilator anymore. The hospitals can only treat patients properly however, as long as they’re not flooded with patients. In the Netherlands, we’re now expecting hospital occupation will exceed the record seen last winter.
The vaccines were supposed to allow us to return to normal. If 85% of adults are vaccinated, 95% of all elderly are vaccinated and we have more patients in the hospitals than we did during the previous winter, then it’s time to admit that the vaccines have failed. If we deploy boosters we will merely double down on the original mistake. Until people can admit that these vaccines have failed, the situation is just going to get worse.
Excellent writeup. Keep up the good work sir.
Excellent work. I have been following the numbers published every Thursday by the RKI in Germany for the last 2 months. I am watching the numbers for > 60 years old (my category), specifically for % of those who have died from/with COVID that are ‘fully’ vaccinated. On October 14 the was: 34.7%. On November 11, the number had grown to 44.1%. Waiting for today’s report to see if the trend continues.
Has anybody else noticed how the Astra Zeneca concoction has been quietly dropped? It’s rMNA all the way now, and if your first 2 shots were Anal Zeneca then you are being topped up with Pfizer or Murderna. This is one example of the narrative being subtly changed. But I’m afraid they are far from admitting the quackcines have failed – in fact they are doubling down and bringing in quite terrifying totalitarian measures to cow the population into compliance. I’m finding it increasingly hard to attribute this to scientific / political / medical hubris alone. Any ideas on how we get through this accursed period of history will be greatly appreciated.
>I’m finding it increasingly hard to attribute this to scientific / political / medical hubris alone.
That’s a tough one. I’m still inclined to blame incompetence and mass hysteria for this disaster, but I can see why it’s hard to believe. It’s hard for most people to realize just how incompetent most people in power truly are. They’re highly socially competent, but extremely bad at understanding the problems they have to make decisions on.
If I’m at the top of a mountain, packing a snowball, I might kick it down the mountain and start events in motion that I don’t otherwise control. But I provided the impetus and general direction.
There are undoubtedly a great deal (majority) of middle manager class types and politicians who are incompetent. And mass formation / hysteria is a key factor.
But I don’t think that explains the whole power dynamic and unfolding events we have seen lately.
There seems to be a need to pivot to some new kind of economic system that is not reliant on infinite growth with a finite resource base. And there are individuals and factions with great wealth who arguably have a strong incentive to execute a controlled demolition of the global economy, so that they maximize their chances of remaining on top in whatever new paradigm emerges.
Parts of this pandemic and coordinated global response give the impression that there are people packing snowballs at the top of the mountain, and the incentive would exist for them to do so.
No, not every nook and cranny the ball rolls into is controlled. But it doesn’t have to be. The general direction and Overton window is set.
I’d agree with that take too. But, there are always a few that given the opportunity will give it a try.
Yes, it is a combination of the people in power being incurable goobers and also being unable to admit they were wrong, instead choosing every time to double down on stupidity. This inability to adapt or course-correct is why, combined with energy descent and all the rest of the onrushing crises that mankind cannot control, I think that the next 10 or 20 years could be apocalyptic with collapsing or failed states worldwide, mass mortality, and hardship on a scale not seen in a long time. This is not intended to be a gloom and doom assessment, it’s just that I don’t see any of this ending well. The global system was in trouble well before COVID and now there is no fixing it.
From the second I heard about the mRNA vaccines, I was saying, it is unwise to try a medication with a novel mechanism of action, during an emergency.
You don’t respond to emergencies with novelty fixes, you respond to them by sticking to your standard operating procedures with monk-like discipline, because they are the robust and time tested solutions for similar problems in the past.
Their fancy fixes amount to taking risky gambles on unproven bullshit, right when reliable and proven solutions are what is needed most.
That’s what they did with this vaccine. They could’ve done live attenuated, they could’ve done heat killed, they could’ve done something that actually had a long track record of solving the fucking problem.
Instead, they did leftism.
Perhaps the piece of the puzzle we’re missing is extremely banal: Curing disease is not really financially viable in the long run. What’s financially viable is making disease manageable.
You know what’s financially viable?
A new injection every three months. A lifetime subscription model. An industry of people whose job it is to spend their whole day sticking swabs up our noses, to figure out which variant is going to show up this winter and how the vaccines will have to be adjusted for it.
Oh you didn’t take your booster for the Mu version that’s going to be dominant this winter? Well that means you’re stuck with our Delta booster from last year, which means you’re going to die from antibody dependent enhancement!
History shows us that most real conspiracies are very banal: People want to earn money. Moderna was a company that had no product, the mRNA therapies they were developing went nowhere.
You get yourself some six figure salary lobbyists and you let them convince the regulators that only your spike-protein based vaccine can safely defeat this dangerous new virus, all the other vaccine candidates are very dangerous and won’t work!
And so we end up with the mysterious situation where China and India have inactivated vaccines, while we somehow got stuck with the mRNA/Adenovirus junk that merely makes the situation worse.
It could be very simple: In our hybrid market system in which most people now struggle to afford anything beyond food and rent, our governments are the teats that deliver an endless supply of milk to every pharmaceutical corporation and defense contractor out there.
When they see a teat, they make a plan to latch onto it forever.
This is highly realistic.
The media also tries to make a panic out of everything, and goes with whatever sticks. Same scam, different industry.
For what it’s worth I am not generally against vaccines. I’d take an inactivated vaccine, if I for some reason could not avoid the need to take some kind of covid vax. It would of course be retarded, said vaccine would wear off really fast due to mutation, but I mean it as a matter of practicality if it became some administrative hurdle to clear to get my rights back.
Until then, and so long as I can get away with it, I’m just not gonna take it. Ugh, I know!!!
There was never going to be any way for them to make a targetted vaccine for new variants. Sure, they claimed they could as part of their marketing BS, but it was never possible. Why? Because each of the variants are too distinct from each other… so if you target just 1 particular new variant (Delta+), you become fully vulnerable to Alpha, Gamma, Epsilon, Lamda, Lambada etc. So that was another false sell that was propagated, and the reason why even though we’re now dealing with Virus Version 2021(D), we’re still using Jab 2019(A).
I posted this on another comment thread earlier today… my MIL – unthinking following of all govt policies, went for her booster (P) in the first week of Oct. She came down with Covid over the weekend, so it’s just over 1 month and the booster didn’t even have any protection against infection that quickly? We are 100% masked up in Singapore. 10% of the hospitalized vexed cases are now of the boosted variety… including the folks in ICU. Overall 20% boosted. So the ratios are quickly converging in just over 1 month of boosting. MIL is a super healthy early 70’s lady, no recognized health issues.. so she shouldn’t have caught it that easily, unless the vex is doing a real number on her immune system now.
Again, great article, exec summary “shitty antibodies”, and for anyone still on the fence, they are persisting (with OAS) this scam-demic to achieve this:
Seen this Radagast?
No I hadn’t thanks. This actually fits what other vaccine developers were warning about last year.
You may live to see man-made horrors beyond your comprehension. Well, I guess I did.
What caused the drop off in covid deaths in the UK around March 2021?