Mass vaccination with leaky vaccines leaves SARS-COV-2 with no other path towards survival than for it to evolve to use our vaccine induced immune response to its own advantage. Because there’s an enormous cohort of people in the Western world with similar immunity to one another because of the vaccines, that’s the niche this virus now begins to adapt to.
The problem with these vaccines is that they generate a response to an identical version of the spike protein in every single person who receives them. It’s the equivalent of a village where everyone installs the same lock on their door: The burglars now just have to work on developing one particular key.
If you make the whole population’s immunity dependent on one particular protein of one particular variant of a novel virus, you put our collective immunity at a tremendous disadvantage in the arms race that is inevitably going to take place against this virus.
As we’re left with fewer vaccine induced antibodies that still work against Omicron, evolutionary pressure to overcome the last few antibodies too increases dramatically. That’s why you see the following problem:
Here are calculated binding scores (see https://t.co/jIPbndSdqp to mouse over points for mutations). BA.2 calculated to have *less* antigenic escape than main BA.1 lineage. BA.1 + R346K has *more* escape, also worse than @PaulBieniasz @theodora_nyc polymutant (PMS20). (6/n) pic.twitter.com/G5zW19Ei9w
— Bloom Lab (@jbloom_lab) December 13, 2021
A few months ago virologists came up with a hypothetical coronavirus that almost completely escapes the vaccine induced immune response. Nature then came up with a version that’s even more capable of escaping the vaccine. It’s called “BA.1 + R346K”. It won’t shock you, to hear that this version of Omicron is rapidly becoming more common:
That’s the problem you’re dealing with: Any study claiming that boosters work against the latest variant always looks at the past and can’t tell you how the situation will change in response to its widespread deployment.
But in Denmark something worse is apparently happening. Omicron was capable of entirely replacing Delta in a matter of weeks. This demonstrates a big reproductive advantage. But now it’s apparent that there’s a different variant of Omicron, that has entirely replaced the original Omicron seeded in Denmark in just four weeks:
Its name is BA.2 and all the evidence would suggest it’s better adopted to spreading in humans than the version people were studying. This is what I warned about a few weeks ago: If Omicron evolved in mice, then after its jump into humans you’ll witness it shed those mutations that favor replication in mice at the cost of replication in humans.
It leads to this epic hockeystick:
You can take a look at the mutation profile of BA.2 here.
Almost everything we know about Omicron is about BA.1, the standard version. BA.2 looks very different and is probably going to show up everywhere in the coming days, it’s already widespread in Denmark and Sweden.
What seems to have happened is that governments have thrown in the towel: Everything they threw at this virus failed to make a difference (or made it worse and had to be covered up), so now they finally want to get people to accept it as part of life.
But for that to happen, requires a population that develops herd immunity against the virus. It should be pretty clear at this point, that no such herd immunity has developed so far. We are seeing more people getting infected than ever before. They are barely testing people in the Netherlands now, but yesterday we had more people who tested positive than at any previous point in time, despite testing far fewer people.
Why is the population not developing immunity against this virus? What is stopping us from bringing this misery to an end? This is an important question to answer. You can look at all the evidence, most Western countries are now starting to report that vaccinated people have a higher chance of catching Omicron than unvaccinated people. Some studies report that boosted people do have a lower chance of catching it, but this probably mainly reflects behavioral differences: The boosted people are really scared of SARS-COV-2, so they take far more effort to avoid interactions that can cause them to get infected.
The only continent that seems to be spared by SARS-COV-2, is the only continent that’s not vaccinated. Scientists are looking at a mystery: How did Africa avoid a covid catastrophe? We see this pattern everywhere. Highly vaccinated countries are having continual outbreaks of this virus. The reason is relatively simple: It’s much easier for evolutionary processes to overcome homogeneous Spike-directed immunity, than for evolution to overcome the diverse natural immunity developed through infection from multiple variants.
In highly vaccinated populations, a new variant with a handful of Spike mutations will be the equivalent of a burglar who stumbles upon a key that opens all the locks in the village. In populations with high levels of natural immunity, there is no magical key that opens all the locks: One person’s immune response is focused on the Nucleocapsid protein, another person’s response on the Membrane protein, yet another person’s response is focused on the Spike protein. One person has experience with the Spike mutations from Delta, yet another person developed his immunity from Alpha.
No matter what new outfit the virus wears, people will always be recognizing parts of it. In contrast, the vaccine is the equivalent of telling people to look for a burglar who wears round sunglasses. The booster should be considered the equivalent of telling people who realized after encountering him that he also carries a big bag with him: “No, no, forget about that big bag with tools, you’re mistaken. Remember, I told you: It’s the sunglasses you need to be looking for.”
In addition, the Spike protein that vaccinated people learn to recognize is an artificially stabilized one. This leads to a situation where the immune system recognizes just a handful of epitopes on the Spike protein. In contrast, natural infection leads to a wider range of epitopes on the Spike protein that are recognized, because naturally infected people’s immune systems encounter the protein in two different configurations: Open and closed.
Once the governments began with this vaccination program, all bets were off. Whereas every previous new virus that jumped the species barrier into human beings ultimately died out or became endemic through diverse widespread natural immunity, for the first time in human history, we decided to intervene in this process and endowed everyone with a very similar artificial immune response to a tiny part of the virus that rapidly changed to use that artificially induced immune response to its own advantage.
With natural immunity in healthy people with properly functioning immune systems, subsequent infections become milder. A reinfection has a 90% reduced risk of leading to hospitalization. That’s why South Africa had such a mild Omicron wave. Breakthrough infections on the other hand, when the virus bashes through your artificially induced immune response, are often severe.
I can’t emphasize this enough: In South Africa, Omicron was a nothingburger. So why is it not a nothingburger in Europe? Why is it not a nothingburger in the United States?
You’re dealing with a self-inflicted wound.
As long as the population keeps taking these vaccines, the population remains sitting ducks for versions of this virus that use the vaccine induced immune response to their own advantage. Fool our immune systems into thinking they need to be looking for an old version of the Spike protein and the population becomes sitting dicks for whatever new variants of this virus emerge.
But if you really want to understand what’s happening, the place to look is Israel. Israel is ahead of the rest of us because they began administering boosters earlier and what do we see?
A record number of infections, with no end in sight. Remember how they wrote “this is really a three dose vaccine“? Well, if you look at Israel, you’re still screwed even after three doses of the vaccine, because the booster’s effect only lasts for a few months.
Vaccination however is subject to diminishing returns. Consider this study in the Influenza vaccine. After three previous doses of the seasonal influenza vaccine, the vaccine’s effectiveness drops dramatically in healthy young Japanese teenagers. The effect is seen in the elderly too, where every successive vaccine’s efficacy is interfered with by every previous vaccine:
We included 58,304 testing episodes for respiratory viruses, with 11,496 (20%) testing positive for influenza and 31,004 (53%) vaccinated. Adjusted VE against laboratory-confirmed influenza for the six seasons combined was 21% (95% confidence interval (CI): 18 to 24%). Patients who were vaccinated in the current season, but had received no vaccinations in the previous 10 seasons, had higher current season VE (34%; 95%CI: 9 to 52%) than patients who had received 1–3 (26%; 95%CI: 13 to 37%), 4–6 (24%; 95%CI: 15 to 33%), 7–8 (13%; 95%CI: 2 to 22%), or 9–10 (7%; 95%CI: −4 to 16%) vaccinations (trend test p = 0.001).
Vaccines also interfere with each other. The influenza vaccine increases the risk of admission for non-influenza respiratory infections. So, the Dutch government apparently wants to inject everyone with another three shots in 2022. Has anyone ever considered the possibility that this problem doesn’t have a cheap and easy techno-fix?
Has anyone ever considered the fact that the human body has limited immunological capacity? What happens if you start giving us three shots every year against whatever you expect the latest variant of corona to be? You need your immune system not just for pathogens, but also to clean up internal damage.
Corona viruses are flexible and generally constantly reinfect us every winter. SARS-COV-2 is no different. If everyone has an identical vaccine induced immune response against an old version of the Spike protein of SARS-COV-2, then we’re just making it easier for this virus to reinfect us in a massive sudden wave. That’s what’s now happening. It’s not coincidence that Omicron causes such a massive wave, much bigger than any previous wave.
A proper vaccine would consist of a live attenuated vaccine, administered intranasally, to induce mucosal immunity. To avoid encouraging the virus to overcome this immune barrier, only high risk demographics would be vaccinated.
For younger low-risk people like me, the proper response would be to simply emphasize healthy living and to offer effective prophylactic treatment. SARS-COV-2 can still cause long covid symptoms in young people, but this also happens in people who get infected after being vaccinated. Mass gatherings for young people during the summer should have continued. The summer is the best time for young people to get infected with this virus.
Unfortunately that didn’t happen. They gave everyone these vaccines, which prepare your immune system for an old version of the virus. Many people received these vaccines before ever being infected with the virus, which causes a massive original antigenic sin response, as the body is hampered in developing a proper immune response against this virus. Others have had natural infections, but received boosters afterwards that reduced the breadth of their immune response.
We’ve now had a big wave of BA.1 Omicron, but now we’re going to see the next wave, of BA.2 Omicron. And when we do, it’s going to become rather painfully obvious that these Omicron variants only cause issues in highly vaccinated populations.
What I wonder is: When do people who have now received three injections against a virus that still ends up infecting them and making them sick start asking the hard questions?
Thank you for doing this analysis. Do you have any idea what the severity of BA.2 is? Also, what happened to the multiple vaccinated Japanese in terms of flu severity and or all cause mortality?
>Thank you for doing this analysis. Do you have any idea what the severity of BA.2 is?
We have no studies so far on this, but if you follow hospitalizations in Denmark in the coming days then you should be able to get a rough indication of its severity.
Thanks for explaining it so nicely.
We gave the virus a optimal solution to aim for and lo and behold it took it.
It will be interesting to see if vaccinated will still be able to learn to defend themselves against this variant.
As long as we continue vaccinating people, this will go on. Any newly vaccinated person becomes fodder for this virus. We are feeding it.
Thanks for this update. The more I see governments pushing these clearly neither safe or effective injections into their populations, the more it looks criminal. It’s particularly depressing to see stats from the UK showing that up to 30,000 people are still getting a daily first dose of these shots. Talk about being late to the party. Is there any assessment yet on BA.2’s ability to breakthrough the ‘vaccines’ compared to the first Omicron variant?
>Is there any assessment yet on BA.2’s ability to breakthrough the ‘vaccines’ compared to the first Omicron variant?
Well, considering it has replaced BA.1 in highly vaccinated Denmark, it would be reasonable to expect it to have greater capacity to cause breakthrough infections.
So far there’s no data yet though. Everyone is still focused on BA.1.
Thank you for this. You’ve become an invaluable resource to stay abreast of the most up-to-date scientific developments regarding the pandemic, especially for someone like me who does not spend time on Twitter. Appreciate that you always cite sources for further reading and reflection, and make your reasoning clear and easy to follow.
Let us know if you change your mind about accepting paid support from your readers. I’d be happy to sign up.
In my part of the world, British Columbia, it appears some people are asking hard questions, as it was announced by a state broadcaster that less than half the underage population has enquired or taken any quasi vaccination. But plenty of the opposite type of coverage as well.
On the more personal side, I just gave notice I declined any vaccine or passport for now. Guess I’m an ex government official now, curious how this will all go. Will report back with anything interesting. Some people have reported threats, others just indifference from senior management, some have had staff try to convince them, while the Union called people racists and Nazis. Interestingly, I do know an old colleague went to the COVID policy department, maybe they’ll bring her out to convince me.
Fellow BC employee here! I just submitted my Decline to Declare notification today (today was our deadline to declare our vax status – I’m in a Crown corporation, rather than a regular ministry employee, so slightly behind you). I am wondering what the next step will be too. I am part of a small group on Telegram of employees in my institution who are resistant to being vacced. We are all doing our declarations today. At least one is a single mother, and I think she’s going to try the religious exemption route. I hope it works for her.
I’m so appalled by the way this has all been handled, and have lost all respect for my government, and the institution I work for that at this point, I’m just waiting out of curiosity to see how they will go about showing me the door. I don’t even want to be here anymore. I’d rather work as a dishwasher, or live out of a car and learn to forage, than bow down to this medical tyranny.
That’s rough. No news on my end, if you want to get in touch ever, let me know.
Sure, send me an email and we could find out if we’re in the same city/region:
Anybody who knows anything about human biology will know that the immune system has limited capacities, and that the generation of large amounts of antibodies comes at a cost. This is why we have an innate immune system. Arguably, antibodies are the WORST method of fighting disease, because they are only necessary once a virus has taken hold in our body, and they are extremely costly to produce. Why do you think antibody titers decrease with years passing? It’s because the body isn’t stupid. That besides, even small amounts of residual antibodies serve as blueprints and help accelerate the acquired immune reaction. This is also why constant re-vaccination is so ridiculous: it basically just trains the body to rely on artificially high levels of (ineffective) vaccine-acquired antibodies, and reduces its ability to build natural and more wholesome antibodies. Usually, antibodies against respiratory diseases are updated yearly by infections with mild or no symptoms, as the viruses mutate. This process is clearly weakened by constant re-vaccination, as energy is wasted on old antibodies, which in turn increases dependency on vaccines. It’s a self-fulfilling prophecy, and they want us all to partake in it.
Just today, I found a smoking gun: a website powered by the German government claims that severe side effects of the vaccine are “extremely rare”. They define “severe” as “life-threatening or deadly” and “extremely rare” as “only 0.02% or 1 in 5000”. This is on a per-dosage basis, meaning that after three doses any person’s chance is 1:1666. That’s an incredibly high number. For flu vaccines and others, deaths are usually limited to anaphylaxis, which has a rate of one in multiple hundred thousand doses.
>Anybody who knows anything about human biology will know that the immune system has limited capacities, and that the generation of large amounts of antibodies comes at a cost. This is why we have an innate immune system.
Yeah it amazes me that people seem to think that antibodies wane for seemingly no other reason that our immune system being flawed.
Almost the entire spike protein in the original Wuhan version of this virus displays strong homology to various proteins in our own bodies.
I think antibodies wane for a reason.
“Almost the entire spike protein in the original Wuhan version of this virus displays strong homology to various proteins in our own bodies.”
Yes, this is a fact that is never mentioned in the MSM, and when I bring it up with the doctors I know, several in my family, all I’ve gotten is blank stares. They can’t wrap their heads around the auto-immunological implications of training our immune system to produce antibodies that have a high probability of being able to cross-react with our own bodily tissues.
I think auto-immunological mechanisms underlie the macrophage activation present in severe disease, and also many of the side-effects to these quasi-vaccines.
Have you got a source for me to refer to for this?
Is the point of any vaccine not to create memory T-cells ,’the blueprint’, that would eventually help us when we get re-infected?
Fundamentally is a vaccine not the virus itself which can be used to trigger an immune response by our innate immune system and produce T-cells that eliminate and store the required cells necessary to kill them?
Thank you, an excellent piece. What a mess they have made. I’m so glad I’m vaccine (lol) free
Small world! Another BC employee here. I am in the post-secondary sector, and my employer did not require vaccination or declaration. There was a small push by my Union in September, but I think enough vocal people from both cohorts (jabbed and unjabbed) brought them to their senses. One of my coworkers may have had a vaccine-related fatality in the family, but we’ll never really know. Differently from the Fall term, this term I’m hearing accounts from faculty that there are many more students calling in sick in my institution. On the other hand, I have a buddy that was until recently a commercial pilot. He never took the jab, had to go on a leave, and used banked sick days to pay for training and licensing as a truck driver. He went to “Jabless Jobs” site, and I believe he got a gig driving within Canada. Will know more this weekend.
The main problem for us is the globalist prick in Ottawa. He needs the freaking vax passport to continue implementing the globalist agenda and to push social credit even further.
Interesting, sorry to hear about that person though. If you want to get in touch, let me know.
Sure, send me an email and we could find out if we’re in the same city/region:
Whoops! I didn’t mean to post that twice!
But now that I’m commenting again, I see in the breaking local news that our health regions closures on gyms, fitness, dance, yoga studios, bars, etc have just been extended, with NO end date this time. They say there were 376 cases traced back to gyms in 2021 in my health region (Island Health). The only people who have been allowed in such places for months now, are fully vacced, so we can’t be blamed. But we will be blamed anyway, in all likelihood!
And then there’s the trucker restrictions that just came in, and there are already a LOT of empty holes in the supermarket shelves. Time to stock up and learn to garden and to forage I guess…
AB.2 prevalence seems to be reducing in % terms in Europe. Might lower concern levels too? Latest here: https://outbreak.info/situation-reports?pango=BA.2&selected=IND&loc=PHL&loc=ZAF&loc=DNK&loc=SWE&loc=NOR&loc=IND&overlay=false
Or maybe not.
Yeah this is almost certainly the next big one. You can get infected with it rapidly after BA.1. It remains to be seen what happens when people get hit with BA.2 during the lymphocytopenia induced by BA.1.
How are they measuring asymptotic cases?
Does such a thing even exist?
An article titled “Omicron: Less Virulent But Still Dangerous” had this to say:
“Omicron’s infectivity stems from a couple of factors. Firstly, it appears to overcome full vaccination and booster shot protection against infection, meaning the virus has more hosts at its disposal. Secondly, Omicron replicates extremely rapidly in the nasopharynx, more so than the strains that came before. Thirdly, Omicron transmits from asymptomatic individuals at a much higher rate than previous strains. For the Delta variant, asymptomatic transmission rates were between 1% and 2.6%. The rate for Omicron is over 30%, according to a study by Garrett et al.”
How do you measure asymptotic cases
Going to do a post on the new fangled oral ‘treatment’?
> When do people who have now received three injections against a virus that still
> ends up infecting them and making them sick start asking the hard questions?
They’ll say: “I am so glad I got vaccinated and boosted. Without it, it would have
been much much worse.”